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Deprescribing: When Stopping Medications Is the Right Choice

When you hear deprescribing, the planned and supervised process of reducing or stopping medications that may no longer be needed or could be doing more harm than good. It's not quitting meds cold turkey—it's a careful, doctor-led plan to simplify your regimen and protect your health. Too many people stay on drugs long after they’re useful, especially as they age or their health changes. This isn’t laziness or ignorance—it’s often because no one ever asked if they still needed them.

polypharmacy, taking five or more medications at once is common in older adults and people with chronic conditions. But each extra pill adds risk: dizziness, falls, kidney stress, confusion, or dangerous interactions. For example, someone on narrow therapeutic index, drugs where tiny changes in dose can cause big effects, like warfarin or lithium might be switched between generic versions without realizing the risk. Even small differences in absorption can throw off their balance. And if they’re also taking a sedating antihistamine for allergies, or a statin that causes muscle pain, the pile just gets heavier.

Deprescribing isn’t about cutting corners. It’s about cutting clutter. Think of it like cleaning out your closet—you don’t keep every shirt you ever owned. You keep what fits, what works, and what you actually wear. Same with meds. A 70-year-old on ten pills might be able to drop three: an old blood pressure med they haven’t needed since their kidney function changed, a sleep aid that’s made them groggy all day, or an acid reducer that’s no longer helping. Studies show people feel better after deprescribing—not worse. Energy improves. Confusion clears. Falls drop. And yes, sometimes switching to a cheaper generic helps—but not if it’s the wrong generic, or if the drug itself should’ve been stopped years ago.

That’s why the posts below cover real cases: when staying on brand mattered for stability, when switching generics triggered warning signs, how antifungals or warfarin interact with other meds, and why pharmacists sometimes recommend authorized generics over regular ones. You’ll see how drug shortages force tough choices, how patent expirations change what’s available, and why storing pills in the bathroom might be the least of your worries when you’re on too many drugs at once. This isn’t theory. It’s daily practice. And if you’re taking more than a few meds, it’s time to ask: do I really need all of them?

Polypharmacy and Side Effects: How Taking Too Many Medications Increases Health Risks
By Cedric Mallister 8 Dec 2025

Polypharmacy and Side Effects: How Taking Too Many Medications Increases Health Risks

Taking five or more medications regularly increases the risk of dangerous side effects, falls, and hospitalizations. Learn how polypharmacy harms health-and what you can do to reduce unnecessary drugs safely.

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