When working with Diclofenac SR, a sustained‑release formulation of the non‑steroidal anti‑inflammatory drug diclofenac, designed to provide steady pain relief over 12‑24 hours. Also known as Diclofenac Sustained Release, it targets inflammation and pain by inhibiting cyclooxygenase enzymes.
Diclofenac SR belongs to the broader class of NSAIDs, drugs that lower prostaglandin production to reduce swelling, fever, and discomfort. These meds are common choices for conditions like arthritis, a joint disease that causes chronic pain and limited movement. While NSAIDs help many people, they also bring a risk of gastrointestinal side effects, such as stomach irritation, ulcers, or bleeding that can be serious if ignored. That's why doctors often pair Diclofenac SR with protective strategies like taking it with food or using a proton‑pump inhibitor.
The "SR" part signals an extended‑release tablet, a dosage form that releases the active ingredient slowly, allowing once‑or twice‑daily dosing instead of multiple shots throughout the day. This convenience can improve adherence, especially for older adults managing several medications.
First, always follow the prescribed dose. Typical adult dosing starts at 50 mg twice daily, but your doctor may adjust based on your condition and kidney function. Second, watch for signs of GI trouble—heartburn, dark stools, or sudden abdominal pain require immediate medical attention. Third, inform your healthcare provider about any existing heart disease, hypertension, or kidney issues; Diclofenac SR can affect blood pressure and fluid balance.
Interaction wise, avoid combining Diclofenac SR with other NSAIDs, anticoagulants, or high‑dose aspirin unless a doctor says it’s safe. These combos can amplify bleeding risk. Alcohol also raises the chance of stomach irritation, so moderation is wise.
For people with mild arthritis, Diclofenac SR often offers smoother pain control compared with immediate‑release tablets that can cause peaks and troughs in blood levels. That steadier profile can mean fewer flares and better daily function.
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